You can remote control WeeChat, by sending commands or text to a FIFO pipe (if option "plugins.var.fifo.fifo" is enabled, it is by default). The FIFO pipe is located in "~/.weechat/" and is called "weechat_fifo_xxxxx" (where xxxxx is the process ID (PID) of running WeeChat). Syntax for the FIFO pipe commands/text is one of following: plugin.buffer *text or command here *text or command here Some examples: nick change on IRC server freenode to "newnick" : $ echo 'irc.server.freenode */nick newnick' >~/.weechat/weechat_fifo_12345 display text on IRC #weechat channel: $ echo 'irc.freenode.#weechat *hello everybody!' >~/.weechat/weechat_fifo_12345 display text on current buffer: $ echo '*hello!' >~/.weechat/weechat_fifo_12345 Warning: this is dangerous and you should not do that except if you know what you do! send two commands to unload/reload Perl scripts (you have to separate them with "\n"): $ echo -e '*/perl unload\n*/perl autoload' >~/.weechat/weechat_fifo_12345 You can write a script to send command to all running WeeChat at same time, for example: #!/bin/sh if [ $# -eq 1 ]; then for fifo in ~/.weechat/weechat_fifo_* do echo -e "$1" >$fifo done fi If the script is called "auto_weechat_command", you can run it with: $ ./auto_weechat_command 'irc.freenode.#weechat *hello'